Interpreting MS/MS Results

Join Brian Searle on an illustrated tour about interpreting MS/MS peptide spectra. On this tour you will first see how you can relate mass spectra to peptides. Next you see why the SEQUEST software was developed to interpret these spectra as peptides. Next you will see other software approaches have been developed and how combining approaches produces even better results.

Interpreting MS/MS Results

Brian leads you over, under, around and through the concepts in this overview of what you can learn about peptides from mass spectrometry -- and how its done. You will learn

  1. Why peptides can be identified from mass spectra.
  2. What motivated the development of Sequest.
  3. How Mascot and X! Tandem differ from Sequest.
  4. Why combining results from searching the same data with different programs is a good idea.
  5. One way of doing this combining.

Brian's PowerPoint presentation is on the right.

PepSeq - Online Peptide Sequencing Simulation Software

Once you've got the general idea from Brian's power point slides, you might want to investigate the online peptide sequencing simulation PepSeq by M.J. Robinson at Monash University in Gippsland, Victoria, Australia.



Download in your choice of PowerPoint or PDF:

> PowerPoint

> PDF

 


   

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