Reproducible LC-MS/MS Proteomics

manually verify

 

MassQC, based significantly on work done by the CPTAC project and NIST, can be instrumental in helping your lab gain a better handle on the reproducibility of your LC-MS/MS proteomics experiments. Monitor and troubleshoot the performance of your LC-MS/MS instrumentation with the new quality control tool.


Understanding proteomics reproducibility

Monitoring LC-MS/MS instrument performance can help you:

 

  • Make more confident protein IDs
  • Gain increased statistical power and fewer spurious differences
  • And, prove to funding agencies & journals you quality of work. These will likely demand proof of it in the future

 

In the accompanying slide show, Brian Searle describes the use of MassQC at the 4th annual CPTC meeting in September of 2010.

Validating Sequence Assignments for Peptide Fragmentation Patterns

by Karen Jonscher, Ph.D.

pdf

(2.8 MB, 31 pages)

Power Point Format

(1.4 MB, 50 slides)

If you don't have Power Point, you can download Power Point Viewer.

Internet Explorer 6.0 format(If you use this, clicking the "Slide Show" button in the lower right corner plays the slide show. These slides will not display properly in other web browsers.)

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