Quotes
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“Scaffold has proven invaluable in helping explain experimental results to our clients from large proteomics experiments. The visualization tools make it easy for our clients to understand complex MS/MS comparative analyses. Additionally, because Scaffold is so easy to use, it has greatly decreased the amount of time that it takes our lab to prepare experiment reports. Scaffold has quickly become our standard method to visualize, validate, and share MS/MS proteomics data with our clients. ”
— Dave Allen
Lab Manager
Proteomic Research Services
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“Compiling
individual data sets to build a proteome database and add statistical
analysis to compiled data sets required months of tedium using current
free-ware and add-on utilities. We recently duplicated these efforts
using Scaffold and were able to compile our database with statistical
analysis within hours. Further, the data loading structure of Scaffold
is dynamic, thus as we gain information on expression profiles we can
update our proteome database. File export functions then allow us to
rapidly annotate this proteome database with descriptors (such as
structural and functional annotations) of the proteins in the database.
In summary, Scaffold has become a significant asset to our research and
reagent discovery program”
— Dr. Karen M . Dobos
Mycobacteria Research Laboratories
Colorado State University
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“As a core lab, one of our missions is to educate and empower end users -- Scaffold is ideal for this purpose. Scaffold presents results in an intuitive and easy-to-understand format, and the free Scaffold viewer enables researchers to view and analyze their own data.”
— Dr. Allis Chien
Stanford University Mass Spectrometry
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 "Scaffold has been a great investment for my facility. It not only allows clients that may not have a deep understanding of mass spectrometry based protein identification to understand our results, but it has also contributed greatly to ongoing research in the facility. Scaffold is a bargain for what it does, and the people at Proteome Software have been very helpful and supportive of our needs."
— Dr. Brett Phinney
UC Davis Proteomics Facility
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“I tried really hard to be as conservative as possible, but I still could not stop Scaffold from improving my results!”
— Dr. Phil Wilmarth
Oregon Health Sciences University
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“After using Scaffold for several months now, I have to say that I have been very impressed with its ease of use, robust features, and stability. Since I am doing several replicate experiments using LC/MS/MS, I generate a substantial amount of spectra, and I especially appreciate Scaffold's ability to easily compare proteins/peptides across multiple samples. Also, since I prefer to inspect and evaluate as many MS/MS spectra as possible, Scaffold's "Spectrum" view makes it easy to quickly evaluate the quality of the spectra, while at the same time providing detailed peak labeling if more careful inspection is required.”
— Todd Greco
Children's Hospital of Philadelphia
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“I can already see that Scaffold is really going to be a help in organizing and reviewing our data.”
— Valerie Cavett
Scripps Florida, a division of TSRI
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“I can certainly see the utility of Scaffold for people who wish to compare results between different search engines. Good collection of info under the links section, by the way.”
— Dr. John Cottrell
Matrix Science
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“Scaffold, along with its statistical evaluation, has given us a way to confidently filter our SEQUEST results. Definitely if you use SEQUEST we would recommend Scaffold to display and organize your results.”
— Dr. Andrew Guzzetta
IonSource |
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“Our group produces large amounts of data that is difficult to control,
catalogue and analyse. To carry out shotgun proteomics techniques we had
to load the MS/MS data manually, which proved both labour intensive and
error prone. We tested 'Scaffold' and found that making comparisons
between our samples was simple and fast. The most impressive part was
that we didn't need to access the help function once, as the software
was so intuitive.”
— Dr Kelvin Cain
Head of Proteomics
MRC Toxicology Unit
Leicester, UK
Please note this is our opinion and is not a recommendation from the MRC
as a whole. We are not part of the University of Leicester, our Unit is on their site.
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“Not just the software itself is super, but also the support is great !”
— Dr. Bas van Breukelen
Utrecht University
The Netherlands |
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"We're currently using Scaffold to assemble Sequest, Mascot and GPM results generated by a novel analysis method of human plasma using two exhaustive immuno-depletion steps. Scaffold has really been useful to pool search results and discriminate between false and true positives."
— Pierre Gagné
CHUL Research Center, Québec City, CANADA
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